Our manufacturing network features 3 dedicated production trains with an aggregate capacity of 400 KL, housing reactors from 250 L to 12,000 L. Designed for flexible scale-up, our site integrates advanced cryogenic systems, multi-tier isolation, and specialized high-containment suites for HPAPIs and targeted linkers.
Scalable Capacity from Pilot Scale to Multi-Ton Commercial Delivery
At Anax Laboratories, our infrastructure is purpose-built to take complex chemical entities from process development into large-scale commercial manufacturing. Combining flexible reaction engineering, robust utilities, and specialized containment suites, our facilities deliver regulatory compliance, operator safety, and batch-to-batch consistency.
Key Facility Metrics
- 400 KL Total Installed Reaction Capacity
- 3 Independent Production Trains
- 250 L to 12,000 L Reactor Scalability (GLR & SSR)
- SafeBridge Cat 3/4 HPAPI High-Containment Suites
Reactor Trains & Scalable Reaction Capacities
- Wide Operational Volume Range: Operating volumes span from 250 L pilot vessels up to 12,000 L commercial reactors.
- Metallurgy & Material Diversity: Outfitted with an optimal mix of Glass-Lined Reactors (GLR) and Stainless Steel Reactors (SS-316L / Hastelloy), enabling harsh, corrosive chemical transformations, high-acid chemistries, and ultra-pure crystallization processes.
- Broad Operating Windows: Capable of handling severe reaction conditions, including deep cryogenic reactions (down to -80°C), pressurized hydrogenations, and high-temperature refux systems (up to +200°C).
Specialized High-Containment Suites (HPAPIs & Potent Intermediates)
Built to manufacture low-OEL molecules, cytotoxic compounds, and highly active pharmaceutical ingredients:
- Engineered Containment: Negative-pressure cleanroom suites equipped with closed-system isolators and split butterfly valves (SBVs) to guarantee containment performance down to nanogram exposure limits.
- Dedicated Air Handling: Single-pass, 100% fresh air HVAC with continuous differential pressure cascades and multi-stage HEPA filtration (safe-change BIBO systems).
- Safe Waste & Deactivation: Dedicated chemical inactivation systems for high-potency mother liquors and wash solvents prior to zero-liquid-discharge (ZLD) effluent treatment.
Advanced Bioconjugation & Linker Capabilities
Tailored infrastructure for the sensitive synthesis and purification of targeting chemistry:
- ADC Linkers & Conjugation Molecules: Modular, cleanroom-grade suites dedicated to multi-step peptide-based linkers, functional spacers, and cleavable triggers requiring precise inert-gas atmosphere and moisture exclusion.
- GalNAc & Oligonucleotide Ligand Delivery: Dedicated low-temperature reaction nodes and precision purification infrastructure to handle complex multi-antennary GalNAc architectures without structural degradation.
Downstream Isolation, Drying & Clean Finishing
- Separation & Solid Handling: Fully enclosed Agitated Nutsche Filter Dryers (ANFDs), Hastelloy centrifuges, and conical vacuum dryers with contained discharge systems.
- Clean Finishing Areas: Controlled ISO Class 7 / Class 8 cleanrooms for final API micronization, jet milling, blending, and sampling under unidirectional laminar airflow (LAF).